pentobarbital will minimize the level or influence of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.pentobarbital decreases amounts of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Sturdy CYP3A4 inducers can reduce panobinostat amounts by ~70% and produce t